So I’ll admit it: it took me a while to even set up a Flickr account, let alone actually use it more than once a season. But the more I finally used it, the more I saw how useful it was, even just for sharing pictures. Prime example: my extended family is huge so for the most recent Special Event, I decided to throw some pictures up on my Flickr page, copy the link into an email, and wait for the comments roll in. No more worrying about email limits, slow downloads, or large attachments.
If you plan on using Flickr for a lot of photos (let’s say, more than 20 because I like that number), I recommend using an uploader tool instead of the web-based method. My personal favorite is the shareware FlickrExport iPhoto plugin from Connected Flow but your mileage may vary. It’s also worth looking into the different privacy levels you can set for your photos, such as restricting access to just people you’ve marked “friends” or “family.” Naming and tagging photos (even in batch-mode) is so easy it’s scary. Don’t forget: you can even make Flickr work with Photobooth.
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It's also worth noting that Connected Flow makes a plug-in that works with Aperture, in case you've graduated from iPhoto.
There's also a great Flickr export plug-in for Aperture, which you can find here.
Just thought I'd mention that you can easily do the same thing with .Mac from apple. Although Flickr is free.... Just thinking out loud. :)
there are some other great options out there..
Firefox Companion
https://addons.mozilla.org/en-US/firefox/addon/4441
oakflickr
https://addons.mozilla.org/en-US/firefox/addon/3359
and then your flickr tools
http://flickr.com/tools/
you know, i've seen flikr over time and watched it change a little, but i still prefer smugmug. smugmug has so much greater customization features that it just flows so much better. but then again, flikr is free for the most part and smugmug is not. i guess you get what you pay for.